The further you go in the story of Death Stranding, the more you will have to unlock equipment to improve the comfort of your deliveries. However, with its asynchronous multiplayer mode, the Death Stranding world can be filled with information and some signs can, in a very relative way, spoil the story for you.
It is possible to be spoiled by some indications that come right after some important events. Kojima Productions has planned everything, since you can disable these signs in the game options. At the very bottom of the game settings, select "hide spoilers". This should save you any disappointment.
