One for All is one of the most-loved limited-time rotating modes among League of Legends fans. Although it does not have the glamor of URF and all its variants, or the novelty of the Ultimate Spellbook mode, we do tend to play a few games of it when it returns every few months.
The premise is simple: each team plays the same champion, which is decided by a vote. The result is interaction that would normally never happen given duplicate champions aren't allowed on teams, and can lead to plays never before seen in League of Legends.
This is precisely what happens with Twitch, an ADC who isn't usually that popular in the game, but one who can wreak real havoc in One for All.
Poison in League of Legends leads to a very peculiar interaction, particularly among Cassiopeia, Teemo and Singed. Twitch could make it easier for Cassiopeia's passive to activate, for example, but it won't work the other way round.
Twitch's E - Contaminate cannot be used to take advantage of other poisons, requiring the champion himself to apply the poison with his basic attacks or W - Venom Cask.
However, in One For All mode, you'll find that any Twitch can apply poison for all the other Twitches to exploit. This makes achieving a pentakill very, very probable in this game mode -- which is exactly what happens in the video above.
Reddit user Rileru achieves a pentakill with a single use of E - Contaminate.
With the hard work done by your teammates to apply the poison, just press a key and enjoy an easy victory!